WP5: Improvement of psychological disturbances through innovative nutritional interventions targeting the gut microbiota
The hypothesis is that nutritional interventions with prebiotics can modulate the levels of neuroactive metabolite(s) (primary objective) and therefore improve psychological outcomes (secondary objective), through modification of the gut microbiota composition
Task 5.1: Clinical study testing the effects of prebiotic supplementation on the metabolic profile and the psychological outcomes in AD patients (Gut2Brain cohort)
Task 5.2: Clinical study testing the effect of prebiotic supplementation combined with a high-fiber diet on the metabolic profile and the psychological outcomes in obese patients (Food4Gut cohort)