WP2: Relevance of the selected neuroactive metabolite(s) in different physiopathological conditions.
We hypothesize that the metabolite(s) selected in the WP1 will be associated with psychological symptoms in obese and aged subjects. The first objective of the WP2 is to test the relevance of the neuroactive properties of the selected blood metabolite(s) in other cohorts of patients presenting different physiopathological conditions (obesity, ageing).The second objective is to identify the potential confounding factors influencing the levels of the neuroactive blood metabolite(s) (nutritional status, inflammatory status, body mass index, metabolic disturbances, and age).
Task 2.1: Extension of the neuroactive properties of the selected metabolite(s) in cohort of obese patients
Task 2.2: Extension of the neuroactive properties of the selected metabolite(s) in a cohort of elderly